Shikonin-induced necroptosis in nasopharyngeal carcinoma cells via ROS overproduction and upregulation of RIPK1/RIPK3/MLKL expression

Objective: Shikonin has inhibitory effects against nasopharyngeal carcinoma that are mediated through the apoptotic pathway. However, necroptosis signaling pathways may enable the elimination of apoptosis-resistant cancers when induced with targeted therapeutic agents. Thus, there is a need to clari...

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Detalles Bibliográficos
Autores principales: Liu, Tiancong, Sun, Xun, Cao, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498394/
https://www.ncbi.nlm.nih.gov/pubmed/31118661
http://dx.doi.org/10.2147/OTT.S200740

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498394/
https://www.ncbi.nlm.nih.gov/pubmed/31118661
http://dx.doi.org/10.2147/OTT.S200740

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