Biomimetic synthesis of the natural product salviadione and its hybrids: discovery of tissue-specific anti-inflammatory agents for acute lung injury

Acute lung injury (ALI) is an inflammatory disease with no effective pharmacological treatment. The therapeutic potential of the anti-inflammatory natural product tanshinone IIA (2) for ALI is seriously impaired by its poor pharmacokinetic (PK) properties. Inspired by the unique benzo[def]carbazole-...

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Detalles Bibliográficos
Autores principales: Ding, Chunyong, Chen, Hongjin, Liang, Bin, Jiao, Mingkun, Liang, Guang, Zhang, Ao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498537/
https://www.ncbi.nlm.nih.gov/pubmed/31123577
http://dx.doi.org/10.1039/c9sc00086k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498537/
https://www.ncbi.nlm.nih.gov/pubmed/31123577
http://dx.doi.org/10.1039/c9sc00086k

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