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Increased proteinase 3 and neutrophil elastase plasma concentrations are associated with non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes

INTRODUCTION: Non-alcoholic fatty liver disease (NAFLD) is becoming a major health problem worldwide. Inflammation plays an important role in disease pathogenesis and recent studies have shown a potential role for the neutrophil serine proteases (NSPs) proteinase-3 (PR3) and neutrophil elastase (NE)...

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Detalles Bibliográficos
Autores principales: Mirea, Andreea-Manuela, Toonen, Erik J. M., van den Munckhof, Inge, Munsterman, Isabelle D., Tjwa, Eric T. T. L., Jaeger, Martin, Oosting, Marije, Schraa, Kiki, Rutten, Joost H. W., van der Graaf, Marinette, Riksen, Niels P., de Graaf, Jacqueline, Netea, Mihai G., Tack, Cees J., Chavakis, Triantafyllos, Joosten, Leo A. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498541/
https://www.ncbi.nlm.nih.gov/pubmed/31046673
http://dx.doi.org/10.1186/s10020-019-0084-3