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miR-27b-mediated suppression of aquaporin-11 expression in hepatocytes reduces HCV genomic RNA levels but not viral titers

BACKGROUND: MicroRNAs (miRNAs) have gained much attention as cellular factors regulating hepatitis C virus (HCV) infection. miR-27b has been shown to regulate HCV infection in the hepatocytes via various mechanisms that have not been fully elucidated. In this study, therefore, we examined the mechan...

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Detalles Bibliográficos
Autores principales: Sakurai, Fuminori, Hashimoto, Rina, Inoue, Chieko, Wakabayashi, Keisaku, Tsukamoto, Tomohito, Imaizumi, Tsutomu, Andres, Taracena Gandara Marcos, Sakai, Eiko, Itsuki, Kanae, Sakamoto, Naoya, Wakita, Takaji, Mizuguchi, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498629/
https://www.ncbi.nlm.nih.gov/pubmed/31046802
http://dx.doi.org/10.1186/s12985-019-1160-6