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miR-27b-mediated suppression of aquaporin-11 expression in hepatocytes reduces HCV genomic RNA levels but not viral titers
BACKGROUND: MicroRNAs (miRNAs) have gained much attention as cellular factors regulating hepatitis C virus (HCV) infection. miR-27b has been shown to regulate HCV infection in the hepatocytes via various mechanisms that have not been fully elucidated. In this study, therefore, we examined the mechan...
Autores principales: | Sakurai, Fuminori, Hashimoto, Rina, Inoue, Chieko, Wakabayashi, Keisaku, Tsukamoto, Tomohito, Imaizumi, Tsutomu, Andres, Taracena Gandara Marcos, Sakai, Eiko, Itsuki, Kanae, Sakamoto, Naoya, Wakita, Takaji, Mizuguchi, Hiroyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498629/ https://www.ncbi.nlm.nih.gov/pubmed/31046802 http://dx.doi.org/10.1186/s12985-019-1160-6 |
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