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Functional characterization of two enhancers located downstream FOXP2

BACKGROUND: Mutations in the coding region of FOXP2 are known to cause speech and language impairment. However, it is not clear how dysregulation of the gene contributes to language deficit. Interestingly, microdeletions of the region downstream the gene have been associated with cognitive deficits....

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Detalles Bibliográficos
Autores principales: Torres-Ruiz, Raúl, Benítez-Burraco, Antonio, Martínez-Lage, Marta, Rodríguez-Perales, Sandra, García-Bellido, Paloma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498672/
https://www.ncbi.nlm.nih.gov/pubmed/31046704
http://dx.doi.org/10.1186/s12881-019-0810-2