Battle of the sexes: contrasting roles of testis-specific protein Y-encoded (TSPY) and TSPX in human oncogenesis

The Y-located testis-specific protein Y-encoded (TSPY) and its X-homologue TSPX originated from the same ancestral gene, but act as a proto-oncogene and a tumor suppressor gene, respectively. TSPY has specialized in male-specific functions, while TSPX has assumed the functions of the ancestral gene....

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Detalles Bibliográficos
Autores principales: Lau, Yun-Fai Chris, Li, Yunmin, Kido, Tatsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Invited Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498724/
https://www.ncbi.nlm.nih.gov/pubmed/29974883
http://dx.doi.org/10.4103/aja.aja_43_18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498724/
https://www.ncbi.nlm.nih.gov/pubmed/29974883
http://dx.doi.org/10.4103/aja.aja_43_18

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