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Transcriptional repression by androgen receptor: roles in castration-resistant prostate cancer
Androgen receptor (AR), a hormonal transcription factor, plays important roles during prostate cancer progression and is a key target for therapeutic interventions. While androgen-deprivation therapies are initially successful in regressing prostate tumors, the disease ultimately comes back as castr...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498738/ https://www.ncbi.nlm.nih.gov/pubmed/30950412 http://dx.doi.org/10.4103/aja.aja_19_19 |