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Apolipoprotein E4 mediates insulin resistance-associated cerebrovascular dysfunction and the post-prandial response

Metabolic dysfunction, commonly a result of diets high in saturated fats and sugar, is associated with impaired cognitive function and an increased risk of age-related cognitive decline (ACD) and Alzheimer’s disease (AD). Compared to the E3 isoform of apolipoprotein (apoE), the E4 isoform is a major...

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Detalles Bibliográficos
Autores principales: Johnson, Lance A, Torres, Eileen Ruth, Weber Boutros, Sydney, Patel, Esha, Akinyeke, Tunde, Alkayed, Nabil J, Raber, Jacob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498752/
https://www.ncbi.nlm.nih.gov/pubmed/29215310
http://dx.doi.org/10.1177/0271678X17746186