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High-throughput quantification of carboxymethyl lysine in serum and plasma using high-resolution accurate mass Orbitrap mass spectrometry

BACKGROUND: Carboxymethyl lysine is an advanced glycation end product of interest as a potential biomarker of cardiovascular and other diseases. Available methods involve ELISA, with potential interference, or isotope dilution mass spectrometry (IDMS), with low-throughput sample preparation. METHODS...

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Detalles Bibliográficos
Autores principales: Rankin, Naomi J, Burgess, Karl, Weidt, Stefan, Wannamethee, Goya, Sattar, Naveed, Welsh, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498755/
https://www.ncbi.nlm.nih.gov/pubmed/30832481
http://dx.doi.org/10.1177/0004563219830432