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Effect of immunosuppressive drugs on cytokine production in canine whole blood stimulated with lipopolysaccharide or a combination of ionomycin and phorbol 12‐myristate 13‐acetate

A pharmacodynamic assay has been previously developed to monitor ciclosporin treatment in dogs by assessing inhibition of cytokine transcription after whole blood stimulation with 12‐myristate 13‐1 acetate and ionomycin (PMA/I). In this study, whole blood stimulation with either PMA/I or lipopolysac...

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Detalles Bibliográficos
Autores principales: Dandrieux, Julien R.S., Narayanan, Lakshmi, Firestone, Simon, Archer, Todd M., Mansfield, Caroline S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498811/
https://www.ncbi.nlm.nih.gov/pubmed/30663866
http://dx.doi.org/10.1002/vms3.143