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Driver genes exome sequencing reveals distinct variants in African Americans with colorectal neoplasia

BACKGROUND: Colorectal cancer (CRC) is the third leading cause of cancer-related deaths in the United States. African Americans are disproportionately affected by CRC. Our hypothesis is that driver genes with known and novel mutations have an impact on CRC outcome in this population. Therefore, we i...

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Detalles Bibliográficos
Autores principales: Ashktorab, Hassan, Azimi, Hamed, Varma, Sudhir, Lee, Edward L., Laiyemo, Adeyinka O., Nickerson, Michael L., Brim, Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498998/
https://www.ncbi.nlm.nih.gov/pubmed/31080553
http://dx.doi.org/10.18632/oncotarget.26721