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Comprehensive Evaluation of the Expressed CD8+ T Cell Epitope Space Using High-Throughput Epitope Mapping

T cell immunity is traditionally assessed through functional recall assays, which detect the consequences of the T cells' antigen encounter, or via fluorescently labeled multimers that selectively bind peptide-specific T cell receptors. Using either approach, if the wrong antigen or peptide of...

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Detalles Bibliográficos
Autores principales: Lehmann, Paul V., Suwansaard, Maneewan, Zhang, Ting, Roen, Diana R., Kirchenbaum, Greg A., Karulin, Alexey Y., Lehmann, Alexander, Reche, Pedro A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499037/
https://www.ncbi.nlm.nih.gov/pubmed/31105686
http://dx.doi.org/10.3389/fimmu.2019.00655