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Polyphosphate as a Target for Interference With Inflammation and Thrombosis

Activated platelets and mast cells expose the inorganic polymer, polyphosphate (polyP) on their surfaces. PolyP initiates procoagulant and proinflammatory reactions and the polymer has been recognized as a therapeutic target for interference with blood coagulation and vascular hyperpermeability. Pol...

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Detalles Bibliográficos
Autores principales: Mailer, Reiner K. W., Hänel, Lorena, Allende, Mikel, Renné, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499166/
https://www.ncbi.nlm.nih.gov/pubmed/31106204
http://dx.doi.org/10.3389/fmed.2019.00076