The Role of Structural Polymorphism in Driving the Mechanical Performance of the Alzheimer's Beta Amyloid Fibrils

Alzheimer's Disease (AD) is related with the abnormal aggregation of amyloid β-peptides Aβ(1−40) and Aβ(1−42), the latter having a polymorphic character which gives rise to U- or S-shaped fibrils. Elucidating the role played by the nanoscale-material architecture on the amyloid fibril stability...

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Detalles Bibliográficos
Autores principales: Grasso, Gianvito, Rebella, Martina, Morbiducci, Umberto, Tuszynski, Jack A., Danani, Andrea, Deriu, Marco A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499180/
https://www.ncbi.nlm.nih.gov/pubmed/31106199
http://dx.doi.org/10.3389/fbioe.2019.00083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499180/
https://www.ncbi.nlm.nih.gov/pubmed/31106199
http://dx.doi.org/10.3389/fbioe.2019.00083

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