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The Role of Structural Polymorphism in Driving the Mechanical Performance of the Alzheimer's Beta Amyloid Fibrils
Alzheimer's Disease (AD) is related with the abnormal aggregation of amyloid β-peptides Aβ(1−40) and Aβ(1−42), the latter having a polymorphic character which gives rise to U- or S-shaped fibrils. Elucidating the role played by the nanoscale-material architecture on the amyloid fibril stability...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499180/ https://www.ncbi.nlm.nih.gov/pubmed/31106199 http://dx.doi.org/10.3389/fbioe.2019.00083 |