CD4(+) T-Cells With High Common γ Chain Expression and Disturbed Cytokine Production Are Enriched in Children With Type-1 Diabetes

The common gamma chain (γ(c)) contributes to the formation of different cytokine receptors [e.g., IL-2 receptor (IL-2R), IL-7R, and IL-15R], which are important for generation of self-reactive T-cells in autoimmune diseases, like in type 1 diabetes (T1D). Whereas, the roles of membrane and soluble I...

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Detalles Bibliográficos
Autores principales: Seyfarth, Julia, Mütze, Nathalie, Antony Cruz, Jennifer, Kummer, Sebastian, Reinauer, Christina, Mayatepek, Ertan, Meissner, Thomas, Jacobsen, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499215/
https://www.ncbi.nlm.nih.gov/pubmed/31110501
http://dx.doi.org/10.3389/fimmu.2019.00820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499215/
https://www.ncbi.nlm.nih.gov/pubmed/31110501
http://dx.doi.org/10.3389/fimmu.2019.00820

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