Cargando…

CD4(+) T-Cells With High Common γ Chain Expression and Disturbed Cytokine Production Are Enriched in Children With Type-1 Diabetes

The common gamma chain (γ(c)) contributes to the formation of different cytokine receptors [e.g., IL-2 receptor (IL-2R), IL-7R, and IL-15R], which are important for generation of self-reactive T-cells in autoimmune diseases, like in type 1 diabetes (T1D). Whereas, the roles of membrane and soluble I...

Descripción completa

Detalles Bibliográficos
Autores principales:	Seyfarth, Julia, Mütze, Nathalie, Antony Cruz, Jennifer, Kummer, Sebastian, Reinauer, Christina, Mayatepek, Ertan, Meissner, Thomas, Jacobsen, Marc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499215/ https://www.ncbi.nlm.nih.gov/pubmed/31110501 http://dx.doi.org/10.3389/fimmu.2019.00820

Ejemplares similares

Next Generation Sequencing Identifies the HLA-DQA1*03:03 Allele in the Type 1 Diabetes Risk-Associated HLA-DQ8 Serotype
por: Enczmann, Jürgen, et al.
Publicado: (2021)

CISH promoter polymorphism effects on T cell cytokine receptor signaling and type 1 diabetes susceptibility
por: Seyfarth, Julia, et al.
Publicado: (2018)

Anxiety, depression, and quality of life in parents of children with congenital hyperinsulinism
por: Roeper, Marcia, et al.
Publicado: (2022)

Risk Factors for Adverse Neurodevelopment in Transient or Persistent Congenital Hyperinsulinism
por: Roeper, Marcia, et al.
Publicado: (2020)

The Common Cytokine Receptor γ Chain Controls Survival of γ/δ T Cells
por: Malissen, Marie, et al.
Publicado: (1997)

Long-term medical treatment in congenital hyperinsulinism: a descriptive analysis in a large cohort of patients from different clinical centers
por: Welters, Alena, et al.
Publicado: (2015)

Treatment with long-acting lanreotide autogel in early infancy in patients with severe neonatal hyperinsulinism
por: Corda, Heike, et al.
Publicado: (2017)

The Role of Cytokines which Signal through the Common γ Chain Cytokine Receptor in the Reversal of HIV Specific CD4(+) and CD8(+) T Cell Anergy
por: Gu, Xiao Xiao Jenny, et al.
Publicado: (2007)

A novel mycobacterial In Vitro infection assay identifies differences of induced macrophage apoptosis between CD4(+) and CD8(+) T cells
por: Nkwouano, Vanesa, et al.
Publicado: (2017)

Memory B-cells are enriched in the blood of patients with acute Buruli ulcer disease: a prospective observational study
por: Adjei, Jonathan Kofi, et al.
Publicado: (2023)

Common gamma chain (γc) cytokines differentially potentiate TNFR family signaling in antigen-activated CD8(+) T cells
por: McNamara, Michael J, et al.
Publicado: (2014)

The Common Cytokine Receptor γ Chain Plays an Essential Role in Regulating Lymphoid Homeostasis
por: Nakajima, Hiroshi, et al.
Publicado: (1997)

Are microRNAs suitable biomarkers of immunity to tuberculosis?
por: Ueberberg, Bianca, et al.
Publicado: (2014)

Human CD8(+)CD28(−) T suppressor cells expanded by common gamma chain (γc) cytokines retain steady allospecific suppressive capacity in vivo
por: Liu, Guihuan, et al.
Publicado: (2020)

Protecting against brain damage by improving treatment in neonates with hypoglycaemia: ProBrain-D—a study protocol of a prospective longitudinal study
por: Hoermann, Henrike, et al.
Publicado: (2022)

Diminished plasma levels of common γ-chain cytokines in pulmonary tuberculosis and reversal following treatment
por: Kumar, Nathella Pavan, et al.
Publicado: (2017)

Characterization of memory T cell subsets and common γ−chain cytokines in convalescent COVID‐19 individuals
por: Rajamanickam, Anuradha, et al.
Publicado: (2022)

Plasma cytokine levels characterize disease pathogenesis and treatment response in tuberculosis patients
por: Vivekanandan, Monika M., et al.
Publicado: (2022)

Hyperinsulinemic Hypoglycemia Associated with a Ca(V)1.2 Variant with Mixed Gain- and Loss-of-Function Effects
por: Kummer, Sebastian, et al.
Publicado: (2022)

A reengineered common chain cytokine augments CD8(+) T cell–dependent immunotherapy
por: Banerjee, Anirban, et al.
Publicado: (2022)

BCG-Vaccinated Children with Contact to Tuberculosis Patients Show Delayed Conversion of Mycobacterium tuberculosis-Specific IFN-γ Release
por: Owusu, Dorcas O., et al.
Publicado: (2023)

Evolution of γ chain cytokines: Mechanisms, methods and applications()
por: Antczak, Magdalena, et al.
Publicado: (2022)

NFAT1 and NFκB regulates expression of the common γ-chain cytokine receptor in activated T cells
por: Shim, Ju A, et al.
Publicado: (2023)

Distinct Roles for Signals Relayed through the Common Cytokine Receptor γ Chain and Interleukin 7 Receptor α Chain in Natural T Cell Development
por: Boesteanu, Alina, et al.
Publicado: (1997)

Interleukin 2, but Not Other Common γ Chain–Binding Cytokines, Can Reverse the Defect in Generation of Cd4 Effector T Cells from Naive T Cells of Aged Mice
por: Haynes, Laura, et al.
Publicado: (1999)

Impact of γ-chain cytokines on EBV-specific T cell cultures
por: Merlo, Anna, et al.
Publicado: (2010)

Rapid Detection and Immune Characterization of Mycobacterium abscessus Infection in Cystic Fibrosis Patients
por: Steindor, Mathis, et al.
Publicado: (2015)

Leukotrienes: Biosynthesis, Metabolism, and Pathophysiologic Significance
por: Mayatepek, Ertan, et al.
Publicado: (1995)

Health Behaviour in Children and Adolescents with Type 1 Diabetes Compared to a Representative Reference Population
por: Kummer, Sebastian, et al.
Publicado: (2014)

IL-2 receptor γ chain cytokines differentially regulate human CD8(+)CD127(+) and CD8(+)CD127(−) T cell division and susceptibility to apoptosis
por: Crawley, Angela M., et al.
Publicado: (2009)

Fueling Cancer Immunotherapy With Common Gamma Chain Cytokines
por: Dwyer, Connor J., et al.
Publicado: (2019)

Synergy between Common γ Chain Family Cytokines and IL-18 Potentiates Innate and Adaptive Pathways of NK Cell Activation
por: Nielsen, Carolyn M., et al.
Publicado: (2016)

The JAK1 Selective Inhibitor ABT 317 Blocks Signaling Through Interferon-γ and Common γ Chain Cytokine Receptors to Reverse Autoimmune Diabetes in NOD Mice
por: Ge, Tingting, et al.
Publicado: (2020)

Advancements of Common Gamma-Chain Family Cytokines in Cancer Immunotherapy
por: Wolfarth, Alexandra A., et al.
Publicado: (2022)

Aberrant cytokine milieu and signaling affect immune cell phenotypes and functions in tuberculosis pathology: What can we learn from this phenomenon for application to inflammatory syndromes?
por: Adankwah, Ernest, et al.
Publicado: (2021)

Common Gamma Chain Cytokines Promote Rapid In Vitro Expansion of Allo-Specific Human CD8(+) Suppressor T Cells
por: Yu, Yuming, et al.
Publicado: (2011)

Decreased Expression of miR-21, miR-26a, miR-29a, and miR-142-3p in CD4(+) T Cells and Peripheral Blood from Tuberculosis Patients
por: Kleinsteuber, Katja, et al.
Publicado: (2013)

The Common Cytokine Receptor γ Chain and the Pre-T Cell Receptor Provide Independent but Critically Overlapping Signals in Early α/β T Cell Development
por: Di Santo, James P., et al.
Publicado: (1999)

Pim1 Reconstitutes Thymus Cellularity in Interleukin 7–And Common γ Chain–Mutant Mice and Permits Thymocyte Maturation in Rag- but Not Cd3γ-Deficient Mice
por: Jacobs, Heinz, et al.
Publicado: (1999)

Analysis of Documentation Speed Using Web-Based Medical Speech Recognition Technology: Randomized Controlled Trial
por: Vogel, Markus, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_8vugntgcvd269qrf481qg27f1p