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Integration of the Deacetylase SIRT1 in the Response to Nucleolar Stress: Metabolic Implications for Neurodegenerative Diseases
Understanding underlying mechanisms of neurodegenerative diseases is fundamental to develop effective therapeutic intervention. Yet they remain largely elusive, but metabolic, and transcriptional dysregulation are common events. Sirtuin 1 (SIRT1) is a nicotinamide adenine dinucleotide (NAD(+))-depen...
Autores principales: | Kreiner, Grzegorz, Sönmez, Aynur, Liss, Birgit, Parlato, Rosanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499230/ https://www.ncbi.nlm.nih.gov/pubmed/31110473 http://dx.doi.org/10.3389/fnmol.2019.00106 |
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