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ATAC-seq reveals regional differences in enhancer accessibility during the establishment of spatial coordinates in the Drosophila blastoderm

Establishment of spatial coordinates during Drosophila embryogenesis relies on differential regulatory activity of axis patterning enhancers. Concentration gradients of activator and repressor transcription factors (TFs) provide positional information to each enhancer, which in turn promotes transcr...

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Detalles Bibliográficos
Autores principales: Bozek, Marta, Cortini, Roberto, Storti, Andrea Ennio, Unnerstall, Ulrich, Gaul, Ulrike, Gompel, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499308/
https://www.ncbi.nlm.nih.gov/pubmed/30962180
http://dx.doi.org/10.1101/gr.242362.118