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Identification of a primitive intestinal transcription factor network shared between esophageal adenocarcinoma and its precancerous precursor state

Esophageal adenocarcinoma (EAC) is one of the most frequent causes of cancer death, and yet compared to other common cancers, we know relatively little about the molecular composition of this tumor type. To further our understanding of this cancer, we have used open chromatin profiling to decipher t...

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Detalles Bibliográficos
Autores principales: Rogerson, Connor, Britton, Edward, Withey, Sarah, Hanley, Neil, Ang, Yeng S., Sharrocks, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499311/
https://www.ncbi.nlm.nih.gov/pubmed/30962179
http://dx.doi.org/10.1101/gr.243345.118