The splicing factor U2AF1 contributes to cancer progression through a noncanonical role in translation regulation

Somatic mutations in the genes encoding components of the spliceosome occur frequently in human neoplasms, including myeloid dysplasias and leukemias, and less often in solid tumors. One of the affected factors, U2AF1, is involved in splice site selection, and the most common change, S34F, alters a...

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Detalles Bibliográficos
Autores principales: Palangat, Murali, Anastasakis, Dimitrios G., Fei, Dennis Liang, Lindblad, Katherine E., Bradley, Robert, Hourigan, Christopher S., Hafner, Markus, Larson, Daniel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499322/
https://www.ncbi.nlm.nih.gov/pubmed/30842218
http://dx.doi.org/10.1101/gad.319590.118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499322/
https://www.ncbi.nlm.nih.gov/pubmed/30842218
http://dx.doi.org/10.1101/gad.319590.118

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