High Hes1 expression and resultant Ascl1 suppression regulate quiescent vs. active neural stem cells in the adult mouse brain

Somatic stem/progenitor cells are active in embryonic tissues but quiescent in many adult tissues. The detailed mechanisms that regulate active versus quiescent stem cell states are largely unknown. In active neural stem cells, Hes1 expression oscillates and drives cyclic expression of the proneural...

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Detalles Bibliográficos
Autores principales: Sueda, Risa, Imayoshi, Itaru, Harima, Yukiko, Kageyama, Ryoichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499325/
https://www.ncbi.nlm.nih.gov/pubmed/30862661
http://dx.doi.org/10.1101/gad.323196.118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499325/
https://www.ncbi.nlm.nih.gov/pubmed/30862661
http://dx.doi.org/10.1101/gad.323196.118

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