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The Influenza A Virus Endoribonuclease PA-X Usurps Host mRNA Processing Machinery to Limit Host Gene Expression

Many viruses shut off host gene expression to inhibit antiviral responses. Viral proteins and host proteins required for viral replication are typically spared in this process, but the mechanisms of target selectivity during host shutoff remain poorly understood. Using transcriptome-wide and targete...

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Detalles Bibliográficos
Autores principales: Gaucherand, Lea, Porter, Brittany K., Levene, Rachel E., Price, Emma L., Schmaling, Summer K., Rycroft, Chris H., Kevorkian, Yuzo, McCormick, Craig, Khaperskyy, Denys A., Gaglia, Marta M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499400/
https://www.ncbi.nlm.nih.gov/pubmed/30995476
http://dx.doi.org/10.1016/j.celrep.2019.03.063