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Relationship between single nucleotide polymorphisms in the 3′UTR of amyloid precursor protein and risk of Alzheimer’s disease and its mechanism

Background and objective: Deregulation of the expression of amyloid precursor protein (APP) can lead to the development of Alzheimer’s disease (AD). Recent studies have shown that many single nucleotide polymorphisms (SNPs) in the 3′ untranslated region (UTR) of APP are associated with the developme...

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Dades bibliogràfiques
Autors principals: Zhou, Qiong, Luo, Lian, Wang, Xiaohang, Li, Xiang
Format: Online Article Text
Idioma:English
Publicat: Portland Press Ltd. 2019
Matèries:
Accés en línia:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499457/
https://www.ncbi.nlm.nih.gov/pubmed/30914454
http://dx.doi.org/10.1042/BSR20182485