Efficient Implementation of Penalized Regression for Genetic Risk Prediction

Polygenic Risk Scores (PRS) combine genotype information across many single-nucleotide polymorphisms (SNPs) to give a score reflecting the genetic risk of developing a disease. PRS might have a major impact on public health, possibly allowing for screening campaigns to identify high-genetic risk ind...

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Detalles Bibliográficos
Autores principales: Privé, Florian, Aschard, Hugues, Blum, Michael G. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2019
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499521/
https://www.ncbi.nlm.nih.gov/pubmed/30808621
http://dx.doi.org/10.1534/genetics.119.302019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499521/
https://www.ncbi.nlm.nih.gov/pubmed/30808621
http://dx.doi.org/10.1534/genetics.119.302019

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