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Efficient Implementation of Penalized Regression for Genetic Risk Prediction
Polygenic Risk Scores (PRS) combine genotype information across many single-nucleotide polymorphisms (SNPs) to give a score reflecting the genetic risk of developing a disease. PRS might have a major impact on public health, possibly allowing for screening campaigns to identify high-genetic risk ind...
Autores principales: | Privé, Florian, Aschard, Hugues, Blum, Michael G. B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499521/ https://www.ncbi.nlm.nih.gov/pubmed/30808621 http://dx.doi.org/10.1534/genetics.119.302019 |
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