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Exosome-based detection of activating and resistance EGFR mutations from plasma of non-small cell lung cancer patients

Non-small cell lung cancer (NSCLC) is the most prevalent form of lung cancer and its molecular landscape has been extensively studied. The most common genetic alterations in NSCLC are mutations within the epidermal growth factor receptor (EGFR) gene, with frequencies between 10-40%. There are severa...

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Detalles Bibliográficos
Autores principales: Castellanos-Rizaldos, Elena, Zhang, Xuan, Tadigotla, Vasisht R., Grimm, Dominik G., Karlovich, Chris, Raez, Luis E., Skog, Johan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499599/
https://www.ncbi.nlm.nih.gov/pubmed/31080561
http://dx.doi.org/10.18632/oncotarget.26885