Efficient delivery of small interfering RNAs targeting particular mRNAs into pancreatic cancer cells inhibits invasiveness and metastasis of pancreatic tumors

We report the use of small interfering RNAs (siRNAs) against ARHGEF4, CCDC88A, LAMTOR2, mTOR, NUP85, and WASF2 and folic acid (FA)-modified polyethylene glycol (PEG)-chitosan oligosaccharide lactate (COL) nanoparticles for targeting, imaging, delivery, gene silencing, and inhibition of invasiveness...

Descripción completa

Detalles Bibliográficos
Autores principales: Taniuchi, Keisuke, Yawata, Toshio, Tsuboi, Makiko, Ueba, Tetsuya, Saibara, Toshiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499602/
https://www.ncbi.nlm.nih.gov/pubmed/31080558
http://dx.doi.org/10.18632/oncotarget.26880

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499602/
https://www.ncbi.nlm.nih.gov/pubmed/31080558
http://dx.doi.org/10.18632/oncotarget.26880

Ejemplares similares