SWI/SNF component ARID1A restrains pancreatic neoplasia formation

OBJECTIVE: ARID1A is commonly mutated in pancreatic ductal adenocarcinoma (PDAC), but the functional effects of ARID1A mutations in the pancreas are unclear. Understanding the molecular mechanisms that drive PDAC formation may lead to novel therapies. DESIGN: Concurrent conditional Arid1a deletion a...

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Detalles Bibliográficos
Autores principales: Wang, Sam C, Nassour, Ibrahim, Xiao, Shu, Zhang, Shuyuan, Luo, Xin, Lee, Jeon, Li, Lin, Sun, Xuxu, Nguyen, Liem H, Chuang, Jen-Chieh, Peng, Lan, Daigle, Scott, Shen, Jeanne, Zhu, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Pancreas
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499717/
https://www.ncbi.nlm.nih.gov/pubmed/30315093
http://dx.doi.org/10.1136/gutjnl-2017-315490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499717/
https://www.ncbi.nlm.nih.gov/pubmed/30315093
http://dx.doi.org/10.1136/gutjnl-2017-315490

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