Cargando…

SWI/SNF component ARID1A restrains pancreatic neoplasia formation

OBJECTIVE: ARID1A is commonly mutated in pancreatic ductal adenocarcinoma (PDAC), but the functional effects of ARID1A mutations in the pancreas are unclear. Understanding the molecular mechanisms that drive PDAC formation may lead to novel therapies. DESIGN: Concurrent conditional Arid1a deletion a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Sam C, Nassour, Ibrahim, Xiao, Shu, Zhang, Shuyuan, Luo, Xin, Lee, Jeon, Li, Lin, Sun, Xuxu, Nguyen, Liem H, Chuang, Jen-Chieh, Peng, Lan, Daigle, Scott, Shen, Jeanne, Zhu, Hao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2019
Materias:	Pancreas
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499717/ https://www.ncbi.nlm.nih.gov/pubmed/30315093 http://dx.doi.org/10.1136/gutjnl-2017-315490

Ejemplares similares

Dissecting the role of SWI/SNF component ARID1B in steady-state hematopoiesis
por: Madan, Vikas, et al.
Publicado: (2023)

Downregulation of ARID1A, a component of the SWI/SNF chromatin remodeling complex, in breast cancer
por: Takao, Chika, et al.
Publicado: (2017)

Preoperative next-generation sequencing of pancreatic cyst fluid is highly accurate in cyst classification and detection of advanced neoplasia
por: Singhi, Aatur D, et al.
Publicado: (2018)

Paraspeckles interact with SWI/SNF subunit ARID1B to regulate transcription and splicing
por: Reddy, Divya, et al.
Publicado: (2022)

SWI/SNF Infobase—An exclusive information portal for SWI/SNF remodeling complex subunits
por: Mani, Udayakumar, et al.
Publicado: (2017)

A new, highly conserved domain in Swi2/Snf2 is required for SWI/SNF remodeling
por: Sen, Payel, et al.
Publicado: (2011)

Chromatin accessibility underlies synthetic lethality of SWI/SNF subunits in ARID1A-mutant cancers
por: Kelso, Timothy W R, et al.
Publicado: (2017)

The Evolutionary Conserved SWI/SNF Subunits ARID1A and ARID1B Are Key Modulators of Pluripotency and Cell-Fate Determination
por: Pagliaroli, Luca, et al.
Publicado: (2021)

LFR Physically and Genetically Interacts With SWI/SNF Component SWI3B to Regulate Leaf Blade Development in Arabidopsis
por: Lin, Xiaowei, et al.
Publicado: (2021)

SWI/SNF proteins as targets in cancer therapy
por: Schiaffino-Ortega, Santiago, et al.
Publicado: (2014)

Architecture of SWI/SNF chromatin remodeling complex
por: Zhang, Zhihui, et al.
Publicado: (2018)

SWI/SNF Alterations in Squamous Bladder Cancers
por: Achenbach, Fabian, et al.
Publicado: (2020)

SWI/SNF Chromatin Remodeling Enzymes in Melanoma
por: Dreier, Megan R., et al.
Publicado: (2022)

Mechanism of action of the SWI/SNF family complexes
por: Chen, Kangjing, et al.
Publicado: (2023)

Advances in the role of SWI/SNF complexes in tumours
por: Li, Ziwei, et al.
Publicado: (2023)

SWI/SNF catalytic subunits’ switch drives resistance to EZH2 inhibitors in ARID1A-mutated cells
por: Wu, Shuai, et al.
Publicado: (2018)

Acute depletion of the ARID1A subunit of SWI/SNF complexes reveals distinct pathways for activation and repression of transcription
por: Blümli, Seraina, et al.
Publicado: (2021)

Corrigendum: LFR Physically and Genetically Interacts With SWI/SNF Component SWI3B to Regulate Leaf Blade Development in Arabidopsis
por: Lin, Xiaowei, et al.
Publicado: (2022)

Reversal of pancreatic desmoplasia by a tumour stroma-targeted nitric oxide nanogel overcomes TRAIL resistance in pancreatic tumours
por: Huang, Hsi-Chien, et al.
Publicado: (2022)

Components of the Human SWI/SNF Complex Are Enriched in Active Chromatin and Are Associated with the Nuclear Matrix
por: Reyes, Jose C., et al.
Publicado: (1997)

The Spectrum of SWI/SNF Mutations, Ubiquitous in Human Cancers
por: Shain, A. Hunter, et al.
Publicado: (2013)

The clinical significance of SWI/SNF complex in pancreatic cancer
por: NUMATA, MASAKATSU, et al.
Publicado: (2012)

Generation of Remosomes by the SWI/SNF Chromatin Remodeler Family
por: Shukla, Manu Shubhdarshan, et al.
Publicado: (2019)

(mis)-Targeting of SWI/SNF complex(es) in cancer
por: Reddy, Divya, et al.
Publicado: (2023)

Cost‐effectiveness of pancreas surveillance: The CDKN2A‐p16‐Leiden cohort
por: Ibrahim, Isaura S., et al.
Publicado: (2023)

The Genomic Landscape of the Fungus-Specific SWI/SNF Complex Subunit, Snf6, in Candida albicans
por: Tebbji, Faiza, et al.
Publicado: (2017)

Disparity in the DNA translocase domains of SWI/SNF and ISW2
por: Dechassa, Mekonnen Lemma, et al.
Publicado: (2012)

Control of LTR transcription by SWI/SNF BAF and PBAF complexes
por: Guendel, Irene, et al.
Publicado: (2014)

The nuclear localization of SWI/SNF proteins is subjected to oxygen regulation
por: Dastidar, Ranita Ghosh, et al.
Publicado: (2012)

SWI/SNF remains localized to chromatin in the presence of SCHLAP1
por: Raab, Jesse R., et al.
Publicado: (2018)

Targeting SWI/SNF ATPases in enhancer-addicted prostate cancer
por: Xiao, Lanbo, et al.
Publicado: (2021)

The SWI/SNF complex in eosinophilic and non eosinophilic chronic rhinosinusitis
por: Kowalik, Katarzyna, et al.
Publicado: (2021)

Chromatin remodeling (SWI/SNF) complexes, cancer, and response to immunotherapy
por: Krishnamurthy, Nithya, et al.
Publicado: (2022)

Emerging Themes in Mechanisms of Tumorigenesis by SWI/SNF Subunit Mutation
por: Jones, Cheyenne A., et al.
Publicado: (2022)

SOX11 regulates SWI/SNF complex components as member of the adrenergic neuroblastoma core regulatory circuitry
por: Decaesteker, Bieke, et al.
Publicado: (2023)

Comprehensive Immunohistochemical Study of the SWI/SNF Complex Expression Status in Gastric Cancer Reveals an Adverse Prognosis of SWI/SNF Deficiency in Genomically Stable Gastric Carcinomas
por: Glückstein, Marie-Isabelle, et al.
Publicado: (2021)

The clinicopathological significance of SWI/SNF alterations in gastric cancer is associated with the molecular subtypes
por: Huang, Shih-Chiang, et al.
Publicado: (2021)

Recent insights into the SWI/SNF complex and the molecular mechanism of hSNF5 deficiency in rhabdoid tumors
por: Kuwahara, Yasumichi, et al.
Publicado: (2023)

Impact of Tumor Grade on Prognosis in Pancreatic Cancer: Should We Include Grade in AJCC Staging?
por: Wasif, Nabil, et al.
Publicado: (2010)

Autoimmune pancreatitis results from loss of TGFβ signalling in S100A4-positive dendritic cells
por: Boomershine, C S, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_3581mls805devvv5rl9ihvjtf1