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Structural and biochemical analyses of the nuclear pore complex component ELYS identify residues responsible for nucleosome binding

The nuclear pore complex embedded within the nuclear envelope is the essential architecture for trafficking macromolecules, such as proteins and RNAs, between the cytoplasm and nucleus. The nuclear pore complex assembly occurs on chromatin in the post-mitotic phase of the cell cycle. ELYS (MEL-28/AH...

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Detalles Bibliográficos
Autores principales: Kobayashi, Wataru, Takizawa, Yoshimasa, Aihara, Maya, Negishi, Lumi, Ishii, Hajime, Kurumizaka, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499780/
https://www.ncbi.nlm.nih.gov/pubmed/31069272
http://dx.doi.org/10.1038/s42003-019-0385-7