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Deletion of exons 17 and 18 in prestin’s STAS domain results in loss of function
Cochlear outer hair cells (OHC) express the motor protein, prestin, which is required for sensitivity and frequency selectivity. Because our previous work showed that a calmodulin binding site (CBS) was located in prestin’s C-terminal, specifically within the intrinsically disordered region, we soug...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499820/ https://www.ncbi.nlm.nih.gov/pubmed/31053797 http://dx.doi.org/10.1038/s41598-019-43343-y |