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Deletion of exons 17 and 18 in prestin’s STAS domain results in loss of function

Cochlear outer hair cells (OHC) express the motor protein, prestin, which is required for sensitivity and frequency selectivity. Because our previous work showed that a calmodulin binding site (CBS) was located in prestin’s C-terminal, specifically within the intrinsically disordered region, we soug...

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Detalles Bibliográficos
Autores principales: Takahashi, Satoe, Yamashita, Tetsuji, Homma, Kazuaki, Zhou, Yingjie, Zuo, Jian, Zheng, Jing, Cheatham, Mary Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499820/
https://www.ncbi.nlm.nih.gov/pubmed/31053797
http://dx.doi.org/10.1038/s41598-019-43343-y

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