Cargando…
Deletion of exons 17 and 18 in prestin’s STAS domain results in loss of function
Cochlear outer hair cells (OHC) express the motor protein, prestin, which is required for sensitivity and frequency selectivity. Because our previous work showed that a calmodulin binding site (CBS) was located in prestin’s C-terminal, specifically within the intrinsically disordered region, we soug...
Autores principales: | Takahashi, Satoe, Yamashita, Tetsuji, Homma, Kazuaki, Zhou, Yingjie, Zuo, Jian, Zheng, Jing, Cheatham, Mary Ann |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499820/ https://www.ncbi.nlm.nih.gov/pubmed/31053797 http://dx.doi.org/10.1038/s41598-019-43343-y |
Ejemplares similares
-
Prestin’s fast motor kinetics is essential for mammalian cochlear amplification
por: Takahashi, Satoe, et al.
Publicado: (2023) -
Prestin Contributes to Membrane Compartmentalization and Is Required for Normal Innervation of Outer Hair Cells
por: Takahashi, Satoe, et al.
Publicado: (2018) -
Susceptibility of outer hair cells to cholesterol chelator 2-hydroxypropyl-β-cyclodextrine is prestin-dependent
por: Takahashi, Satoe, et al.
Publicado: (2016) -
Prestin-Dependence of Outer Hair Cell Survival and Partial Rescue of Outer Hair Cell Loss in Prestin
(V499G/Y501H) Knockin Mice
por: Cheatham, Mary Ann, et al.
Publicado: (2015) -
Cryo-EM structures of thermostabilized prestin provide mechanistic insights underlying outer hair cell electromotility
por: Futamata, Haon, et al.
Publicado: (2022)