Pharmacological systems analysis defines EIF4A3 functions in cell-cycle and RNA stress granule formation

The RNA helicase EIF4A3 regulates the exon junction complex and nonsense-mediated mRNA decay functions in RNA transcript processing. However, a transcriptome-wide network definition of these functions has been lacking, in part due to the lack of suitable pharmacological inhibitors. Here we employ sh...

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Detalles Bibliográficos
Autores principales: Mazloomian, Alborz, Araki, Shinsuke, Ohori, Momoko, El-Naggar, Amal M., Yap, Damian, Bashashati, Ali, Nakao, Shoichi, Sorensen, Poul H., Nakanishi, Atsushi, Shah, Sohrab, Aparicio, Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499833/
https://www.ncbi.nlm.nih.gov/pubmed/31069274
http://dx.doi.org/10.1038/s42003-019-0391-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499833/
https://www.ncbi.nlm.nih.gov/pubmed/31069274
http://dx.doi.org/10.1038/s42003-019-0391-9

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