MicroRNA-125b-5p regulates IL-1β induced inflammatory genes via targeting TRAF6-mediated MAPKs and NF-κB signaling in human osteoarthritic chondrocytes

Abnormal post-transcriptional modulations in inflammatory genes by microRNAs (miRNAs) play a crucial role in human disorders including arthritis. In this study, we determined the effect of hsa-miR-125b-5p on interleukin (IL)-1β induced inflammatory genes in human osteoarthritic (OA) chondrocytes. Bi...

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Detalles Bibliográficos
Autores principales: Rasheed, Zafar, Rasheed, Naila, Abdulmonem, Waleed Al, Khan, Muhammad Ismail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499837/
https://www.ncbi.nlm.nih.gov/pubmed/31053727
http://dx.doi.org/10.1038/s41598-019-42601-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499837/
https://www.ncbi.nlm.nih.gov/pubmed/31053727
http://dx.doi.org/10.1038/s41598-019-42601-3

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