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Brain transcriptome analysis of a familial Alzheimer’s disease-like mutation in the zebrafish presenilin 1 gene implies effects on energy production

To prevent or ameliorate Alzheimer’s disease (AD) we must understand its molecular basis. AD develops over decades but detailed molecular analysis of AD brains is limited to postmortem tissue where the stresses initiating the disease may be obscured by compensatory responses and neurodegenerative pr...

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Detalles Bibliográficos
Autores principales: Newman, Morgan, Hin, Nhi, Pederson, Stephen, Lardelli, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500017/
https://www.ncbi.nlm.nih.gov/pubmed/31053140
http://dx.doi.org/10.1186/s13041-019-0467-y