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A method to reduce imbalance for site-level randomized stepped wedge implementation trial designs

BACKGROUND: Controlled implementation trials often randomize the intervention at the site level, enrolling relatively few sites (e.g., 6–20) compared to trials that randomize by subject. Trials with few sites carry a substantial risk of an imbalance between intervened (cases) and non-intervened (con...

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Detalles Bibliográficos
Autores principales: Lew, Robert A., Miller, Christopher J., Kim, Bo, Wu, Hongsheng, Stolzmann, Kelly, Bauer, Mark S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500026/
https://www.ncbi.nlm.nih.gov/pubmed/31053157
http://dx.doi.org/10.1186/s13012-019-0893-3