Heterogeneity of treatment effect by baseline risk of mortality in critically ill patients: re-analysis of three recent sepsis and ARDS randomised controlled trials

BACKGROUND: Randomised controlled trials (RCTs) enrolling patients with sepsis or acute respiratory distress syndrome (ARDS) generate heterogeneous trial populations. Non-random variation in the treatment effect of an intervention due to differences in the baseline risk of death between patients in...

Descripción completa

Detalles Bibliográficos
Autores principales: Santhakumaran, Shalini, Gordon, Anthony, Prevost, A. Toby, O’Kane, Cecilia, McAuley, Daniel F., Shankar-Hari, Manu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500045/
https://www.ncbi.nlm.nih.gov/pubmed/31053084
http://dx.doi.org/10.1186/s13054-019-2446-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500045/
https://www.ncbi.nlm.nih.gov/pubmed/31053084
http://dx.doi.org/10.1186/s13054-019-2446-1

Ejemplares similares