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Peripheral vascular responses to acetylcholine as a predictive tool for response to cholinesterase inhibitors in Alzheimer’s disease

BACKGROUND: Cholinesterase inhibitors remain the first line therapy for people with mild to moderate Alzheimer’s disease (AD). Response is modest and difficult to predict from pre-treatment characteristics. We hypothesise that skin vascular response to iontophoresis of acetylcholine, which is partly...

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Detalles Bibliográficos
Autores principales: Connelly, Peter J., Adams, Fiona, Tayar, Ziad I., Khan, Faisel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500049/
https://www.ncbi.nlm.nih.gov/pubmed/31053120
http://dx.doi.org/10.1186/s12883-019-1316-4