Knockdown of HMGA2 regulates the level of autophagy via interactions between MSI2 and Beclin1 to inhibit NF1-associated malignant peripheral nerve sheath tumour growth

BACKGROUND: Malignant peripheral nerve sheath tumours (MPNSTs) are sarcomas of Schwann cell lineage origin that occur sporadically or in association with the inherited syndrome, neurofibromatosis type 1 (NF1). This study aimed to examine the function of High mobility group protein A2 (HMGA2) in NF1...

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Detalles Bibliográficos
Autores principales: Yang, Kang, Guo, Wei, Ren, Tingting, Huang, Yi, Han, Yu, Zhang, Hongliang, Zhang, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500071/
https://www.ncbi.nlm.nih.gov/pubmed/31053152
http://dx.doi.org/10.1186/s13046-019-1183-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500071/
https://www.ncbi.nlm.nih.gov/pubmed/31053152
http://dx.doi.org/10.1186/s13046-019-1183-2

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