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Knockdown of HMGA2 regulates the level of autophagy via interactions between MSI2 and Beclin1 to inhibit NF1-associated malignant peripheral nerve sheath tumour growth

BACKGROUND: Malignant peripheral nerve sheath tumours (MPNSTs) are sarcomas of Schwann cell lineage origin that occur sporadically or in association with the inherited syndrome, neurofibromatosis type 1 (NF1). This study aimed to examine the function of High mobility group protein A2 (HMGA2) in NF1...

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Detalles Bibliográficos
Autores principales:	Yang, Kang, Guo, Wei, Ren, Tingting, Huang, Yi, Han, Yu, Zhang, Hongliang, Zhang, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500071/ https://www.ncbi.nlm.nih.gov/pubmed/31053152 http://dx.doi.org/10.1186/s13046-019-1183-2

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