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Mesenchymal Stem Cells Reverse Diabetic Nephropathy Disease via Lipoxin A4 by Targeting Transforming Growth Factor β (TGF-β)/smad Pathway and Pro-Inflammatory Cytokines

BACKGROUND: Diabetic nephropathy (DN) is the leading cause of end-stage renal disease. Mesenchymal stem cells (MSCs) treatment has been proved to be effective in DN models by protecting renal function and preventing fibrosis. However, the underlying mechanism is unclear. Previous research indicated...

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Detalles Bibliográficos
Autores principales: Bai, Yihua, Wang, Jiaping, He, Zhenkun, Yang, Min, Li, Luohua, Jiang, Hongying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500104/
https://www.ncbi.nlm.nih.gov/pubmed/31023998
http://dx.doi.org/10.12659/MSM.914860