Modular, stereocontrolled C(β)–H/C(α)–C activation of alkyl carboxylic acids

The union of two powerful transformations, directed C–H activation and decarboxylative cross-coupling, for the enantioselective synthesis of vicinally functionalized alkyl, carbocyclic, and heterocyclic compounds is described. Starting from simple carboxylic acid building blocks, this modular sequen...

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Detalles Bibliográficos
Autores principales: Shang, Ming, Feu, Karla S., Vantourout, Julien C., Barton, Lisa M., Osswald, Heather L., Kato, Nobutaka, Gagaring, Kerstin, McNamara, Case W., Chen, Gang, Hu, Liang, Ni, Shengyang, Fernández-Canelas, Paula, Chen, Miao, Merchant, Rohan R., Qin, Tian, Schreiber, Stuart L., Melillo, Bruno, Yu, Jin-Quan, Baran, Phil S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500144/
https://www.ncbi.nlm.nih.gov/pubmed/30996125
http://dx.doi.org/10.1073/pnas.1903048116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500144/
https://www.ncbi.nlm.nih.gov/pubmed/30996125
http://dx.doi.org/10.1073/pnas.1903048116

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