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Characterization of apolipoprotein A-I peptide phospholipid interaction and its effect on HDL nanodisc assembly

Background: Synthetic HDLs (sHDLs), small nanodiscs of apolipoprotein mimetic peptides surrounding lipid bilayers, were developed clinically for atheroma regression in cardiovascular patients. Formation of HDL involves interaction of apolipoprotein A-I (ApoA-I) with phospholipid bilayers and assembl...

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Detalles Bibliográficos
Autores principales: Patel, Hiren, Ding, Bei, Ernst, Kelsey, Shen, Lei, Yuan, Wenmin, Tang, Jie, Drake, Lindsey R, Kang, Jukyung, Li, Yaoxin, Chen, Zhan, Schwendeman, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500440/
https://www.ncbi.nlm.nih.gov/pubmed/31118623
http://dx.doi.org/10.2147/IJN.S179837