Cytotoxic and apoptosis-inducing effects of wildtype and mutated Hydra actinoporin-like toxin 1 (HALT-1) on various cancer cell lines

BACKGROUND: Hydra actinoporin like toxin -1 (HALT-1), is a small 18.5 kDa pore forming toxin derived from Hydra magnipapillata which has been shown to elicit strong haemolytic and cytolytic activity when in contact with cell membranes. Due to its cytotoxic potency, HALT-1 was further investigated fo...

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Detalles Bibliográficos
Autores principales: Ng, Teng Jia, Teo, Michelle Yee Mun, Liew, Dek Shen, Effiong, Paul Etim, Hwang, Jung Shan, Lim, Crystale Siew Ying, In, Lionel L.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2019
Materias:
Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500716/
https://www.ncbi.nlm.nih.gov/pubmed/31106043
http://dx.doi.org/10.7717/peerj.6639

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500716/
https://www.ncbi.nlm.nih.gov/pubmed/31106043
http://dx.doi.org/10.7717/peerj.6639

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