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Cytotoxic and apoptosis-inducing effects of wildtype and mutated Hydra actinoporin-like toxin 1 (HALT-1) on various cancer cell lines
BACKGROUND: Hydra actinoporin like toxin -1 (HALT-1), is a small 18.5 kDa pore forming toxin derived from Hydra magnipapillata which has been shown to elicit strong haemolytic and cytolytic activity when in contact with cell membranes. Due to its cytotoxic potency, HALT-1 was further investigated fo...
Autores principales: | Ng, Teng Jia, Teo, Michelle Yee Mun, Liew, Dek Shen, Effiong, Paul Etim, Hwang, Jung Shan, Lim, Crystale Siew Ying, In, Lionel L.A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500716/ https://www.ncbi.nlm.nih.gov/pubmed/31106043 http://dx.doi.org/10.7717/peerj.6639 |
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