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A Lower Maternal Cortisol-to-Cortisone Ratio Precedes Clinical Diagnosis of Preterm and Term Preeclampsia by Many Weeks

CONTEXT: Previous studies have shown reduced placental levels of 11-β-hydroxysteroid dehydrogenase type 2 (11βHSD2) in preeclampsia (PE). However, it is unknown if the maternal cortisol-to-cortisone ratio is predictive of placental complications of pregnancy. OBJECTIVE: To determine the relationship...

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Detalles Bibliográficos
Autores principales: Jayasuriya, Nimesh A, Hughes, Alice E, Sovio, Ulla, Cook, Emma, Charnock-Jones, D Stephen, Smith, Gordon C S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500797/
https://www.ncbi.nlm.nih.gov/pubmed/30768664
http://dx.doi.org/10.1210/jc.2018-02312