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Mutation spectrum of germline cancer susceptibility genes among unselected Chinese colorectal cancer patients

Background: Genetic factors play an important role in colorectal cancer (CRC) risk, yet the prevalence and spectrum of germline cancer susceptibility gene mutations among unselected Chinese CRC patients is largely undetermined. Methods: We performed next-generation sequencing with a 73-genes panel a...

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Detalles Bibliográficos
Autores principales: Gong, Rui, He, Yuan, Liu, Xiao-Yun, Wang, Hai-Yun, Sun, Li-Yue, Yang, Xin-Hua, Li, Bin, Cao, Xin-Kai, Ye, Zu-Lu, Kong, Ling-Heng, Zhang, Da-Dong, Li, Yu-Hong, Xu, Rui-Hua, Shao, Jian-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500872/
https://www.ncbi.nlm.nih.gov/pubmed/31118792
http://dx.doi.org/10.2147/CMAR.S193985