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Mutation spectrum of germline cancer susceptibility genes among unselected Chinese colorectal cancer patients
Background: Genetic factors play an important role in colorectal cancer (CRC) risk, yet the prevalence and spectrum of germline cancer susceptibility gene mutations among unselected Chinese CRC patients is largely undetermined. Methods: We performed next-generation sequencing with a 73-genes panel a...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500872/ https://www.ncbi.nlm.nih.gov/pubmed/31118792 http://dx.doi.org/10.2147/CMAR.S193985 |