Macrocyclic lactone anthelmintic-induced leukocyte binding to Dirofilaria immitis microfilariae: Influence of the drug resistance status of the parasite

The macrocyclic lactone anthelmintics are the only class of drug currently used to prevent heartworm disease. Their extremely high potency in vivo is not mirrored by their activity against Dirofilaria immitis larvae in vitro, leading to suggestions that they may require host immune functions to kill...

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Detalles Bibliográficos
Autores principales: Berrafato, Tessa, Coates, Ruby, Reaves, Barbara J., Kulke, Daniel, Wolstenholme, Adrian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500911/
https://www.ncbi.nlm.nih.gov/pubmed/31054498
http://dx.doi.org/10.1016/j.ijpddr.2019.04.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500911/
https://www.ncbi.nlm.nih.gov/pubmed/31054498
http://dx.doi.org/10.1016/j.ijpddr.2019.04.004

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